Difficile Senses and Hijacks Host Heme

Total sentence count for the succinct summary should be between 5 – 7. 1- Summarize the article by addressing each of the considerations below, but this time for an audience of non-scientists. – Study Design: Describe the overall workflow. What was the plan of attack? – Main Findings: Discuss the most important scientific results. What does the data show? – Significance: Discuss the overall biological importance presented. What is the significance of the study and why should we care? – Future Directions: Describe broad framework for future experimental directions and/or big picture questions. Where does the scientific community go next? 2-Summarize the article by addressing each of the considerations below, but this time for an audience of non-scientists. Use every day words in this summary. -Study Design: Describe the overall workflow. What was the plan of attack? -Main Findings: Discuss the most important scientific results. What does the data show? -Significance: Discuss the overall biological importance presented. What is the significance of the study and why should we care? -Future Directions: Describe broad framework for future experimental directions and/or big picture questions. Where does the scientific community go next? 3-Choose the piece of data that most completely shows evidence for the title of the paper. The piece of data that convinced you. That sold the story. Figures 3A, 5C and 5D are NOT eligible (sorry if you had your heart set on either of those but, don’t fret, there are plenty of good choices) Explain your choice for the most convincing result addressing each of the following considerations: Summary of the experimental approach (workflow) Description of the results Implications of the results for future studies Rationale for your choice. 4- Summarize the modes of action (function) and outcomes for toxins TcdA and TcdB inside professional phagocytes and intestinal epithelial cells. In other words, the intracellular mechanisms by which these toxins mediate pathogenesis, and the effects they have on those host cells. Then, briefly describe the resulting immune response ( 10 sentences minimum)